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Age and Low Fitness Independently Linked to Hidden Heart Rhythm Burden in Healthy Middle-Aged Adults, ESC Study Reports

The findings support screening from about age 50, with confirmation needed in broader, longitudinal research.

Overview

  • Lower aerobic fitness was tied to a notably higher burden of frequent and complex atrial arrhythmias, while advancing age also correlated with ventricular irregularities.
  • Risk climbed roughly 9% per year for atrial and 4% per year for ventricular arrhythmias, with a marked rise beginning around ages 50 to 54.
  • The analysis of 1,151 asymptomatic adults aged 40 to 65 (88% men) used exercise stress testing with continuous ECG monitoring to quantify ectopy burden.
  • Participants with low fitness had an estimated 52% higher risk of irregular heartbeat disorders, according to results presented at ESC Congress 2025 in Madrid.
  • Researchers recommend considering arrhythmia screening from about age 50 and stress that the observational, male‑dominant sample means the results are preliminary and need peer‑reviewed confirmation.