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After Off-Grid Trip, Nobel Medicine Laureate Fred Ramsdell Connects With Committee and Shares Reaction

The immunologist credits shared discoveries on immune regulation with advancing care for autoimmune disease.

Overview

  • The Nobel Assembly’s early-morning call went unanswered as Ramsdell finished a three-week hike with his phone in airplane mode in the Rocky Mountains.
  • His wife, Laura O’Neill, regained cell service near Yellowstone and alerted him after seeing a flood of congratulatory messages.
  • After time-zone delays, he reached Secretary General Thomas Perlmann the next morning, roughly 20 hours after the first attempted call.
  • Perlmann said it was the hardest time he has had reaching a laureate since taking the post in 2016.
  • Ramsdell shares the 2025 prize with Mary Brunkow and Shimon Sakaguchi for work that informs treatment of autoimmune conditions such as some types of arthritis, multiple sclerosis, and Crohn’s disease.