Particle.news

Download on the App Store

AbbVie to Acquire Capstan Therapeutics for $2.1 Billion to Boost In Vivo CAR-T Portfolio

Pending Hart-Scott-Rodino approval, AbbVie will integrate Capstan’s Phase 1 CAR-T candidate with its targeted lipid nanoparticle platform for precise RNA delivery.

Image

Overview

  • AbbVie announced on June 30 that it will acquire Capstan for up to $2.1 billion in cash, pending customary Hart-Scott-Rodino Act antitrust clearance.
  • The agreement covers CPTX2309, Capstan’s Phase 1 anti-CD19 CAR-T therapy aimed at B cell–mediated autoimmune diseases.
  • AbbVie will also gain Capstan’s targeted lipid nanoparticle (tLNP) platform for in vivo RNA delivery to engineer specific cell types.
  • Following the deal announcement, AbbVie shares rose about 0.5% to $183.20 in early trading, reflecting positive investor response.
  • The acquisition positions AbbVie to advance its in vivo cell-engineering programs and supports its strategy to address autoimmune diseases at their root.