Overview

• The trailer offers a tense glimpse of Rose Byrne’s character navigating her daughter’s mysterious illness alongside an absent spouse and a fraught therapist relationship with Conan O’Brien.
• The film premiered at Sundance in January and earned Byrne the Silver Bear for Best Leading Performance at the Berlin International Film Festival.
• Upcoming screenings at the Toronto and New York film festivals will strengthen its awards-season profile ahead of its October 10 theatrical debut.
• Writer-director Mary Bronstein drew on her own caregiving experience and collaborated with producers such as Josh Safdie to craft a visceral, high-anxiety dramedy.
• Unconventional casting—including Conan O’Brien in a serious role and musician A$AP Rocky as a motel neighbor—underscores the film’s blend of dark humor and psychological intensity.