Overview
- Head coach Kyle Shanahan confirmed Brock Purdy will start against Arizona, with Mac Jones returning to the backup role.
- San Francisco waived quarterback Adrian Martinez to open a roster spot and could bring him back to the practice squad if he clears waivers, per team reports.
- Defensive end Clelin Ferrell was signed from the practice squad after recent elevations, with one sack and five tackles logged in his last three appearances.
- Cornerback Eli Apple was elevated as Deommodore Lenoir is questionable with a calf injury and was set for an MRI, with Darrell Luter Jr. a potential fill-in opposite Renardo Green.
- The Cardinals adjusted their roster for the matchup by activating BJ Ojulari, signing Jared Bartlett, and elevating Pharoah Brown and Darren Hill.