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49ers Waive Former First-Round Pick Drake Jackson Following Injury Setbacks

The team moves on from the 2022 draft pick after a failed physical, solidifying rookie Mykel Williams as Nick Bosa’s new counterpart on the defensive line.

Drake Jackson of the San Francisco 49ers walks off the field following a game between the San Francisco 49ers and the Arizona Cardinals at Levi's Stadium on October 01, 2023 in Santa Clara, California.
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Overview

  • Drake Jackson, the 49ers' 2022 second-round draft pick, was waived with a failed physical designation after missing 1 1/2 seasons due to a torn patellar tendon.
  • Jackson’s release clears the way for rookie Mykel Williams, drafted 11th overall in April 2025, to start alongside Nick Bosa on the defensive line.
  • The 49ers bolstered their depth by signing offensive linemen Andre Dillard and Nicholas Petit-Frere, as well as cornerback Dallis Flowers, all on one-year contracts.
  • Jackson initially showed promise with three sacks in the 2023 season opener but failed to record any additional sacks before his injury later that year.
  • The roster overhaul reflects the team’s focus on strengthening its defensive front and addressing gaps ahead of the upcoming NFL season.