Overview
- Brock Purdy (toe) was ruled out on the final injury report, with Mac Jones making his third start of the season.
- San Francisco signed QB Adrian Martinez to the active roster as Jones’s backup and released DL Jordan Jefferson to create the roster spot.
- The team elevated WR Malik Turner and DE Trevis Gipson from the practice squad, leaving five wideouts active for the game.
- Receivers Ricky Pearsall and Jauan Jennings were inactive, with George Kittle still on IR and additional depth pieces unavailable.
- Kickoff at SoFi Stadium was 8:15 p.m. ET on Prime Video, and betting markets had the Rams favored by more than a touchdown.