Overview
- San Francisco named seven inactives for Week 8, including QB Brock Purdy (toe) and C Jake Brendel (hamstring) alongside Bryce Huff, Yetur Gross-Matos, Ricky Pearsall, Jordan James and C.J. West.
- To bolster depth, the 49ers used standard practice-squad elevations on DL Trevis Gipson and OL Nick Zakelj for the matchup in Houston.
- Rookie wide receiver Jordan Watkins suited up and is making his NFL debut.
- During the game, LB Dee Winters (knee) and DT Jordan Elliott (ankle) were ruled out, and DE Sam Okuayinonu was listed as questionable with an ankle injury.
- Matt Hennessy starts at center with Zakelj backing up after Brendel’s ruling, Spencer Burford was downgraded to out, and Kyle Shanahan said Brandon Aiyuk’s practice window could open next week.