Particle.news
Download on the App Store
30 ARTICLES
·
54m ago

49ers Rule Out Purdy, Jennings and Pearsall for TNF at Rams With Mac Jones Starting

Injuries shifted betting odds toward Los Angeles.

Image
Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) runs the ball during the first half against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images/ File Photo
Los Angeles Rams linebacker Jared Verse, left, and linebacker Byron Young celebrate a tackle during the first half on Sept. 21 in Philadelphia. 
49ers quarterback Mac Jones will face a fierce Rams pass rush while dealing with a nagging knee injury that requires a brace, limiting his mobility. 

Overview

  • The 49ers’ final report ruled out QB Brock Purdy (toe) and WRs Ricky Pearsall (knee) and Jauan Jennings (ankle/rib), and Mac Jones — 2-0 in earlier spot starts — will start.
  • San Francisco also remains without TE George Kittle (IR) and WR Brandon Aiyuk (PUP), further thinning its group of pass-catchers.
  • The Rams listed RT Rob Havenstein (ankle) and TE Tyler Higbee (hip) as doubtful, with the rest of their reported injuries trending positive.
  • Both teams are 3-1, and SportsLine’s model projects an 18 percentage-point playoff-probability drop for Los Angeles with a loss and a 14.8-point rise for San Francisco with a win.
  • Sportsbooks lengthened the Rams’ spread after the 49ers’ injury news, and expert pick roundups show most analysts siding with Los Angeles.