Overview

• The 49ers downgraded quarterback Brock Purdy (toe) and wide receiver Jauan Jennings (shoulder, ankle) from questionable to out hours before kickoff against the Cardinals.
• Mac Jones will make his second straight start, with practice-squad elevation Adrian Martinez serving as the backup.
• San Francisco’s receiving options are limited with George Kittle on injured reserve and Brandon Aiyuk on the PUP list, prompting a standard elevation for wideout Malik Turner.
• Jones is coming off a 26-of-39, 279-yard, three-touchdown performance in last week’s win over the Saints.
• NFL Network’s Ian Rapoport reported Purdy could be in line to return in Week 4 if his recovery continues to progress.