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1h ago

49ers Rule Out Brock Purdy for TNF at Rams With Mac Jones to Start

Bookmakers now favor Los Angeles following San Francisco's final injury report.

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This first-down scramble in the first half against the Jacksonville Jaguars on Sunday at Levi’s Stadium may have been when 49ers quarterback Brock Purdy re-aggravated the injury to his big toe.
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Will Kyren Williams and the Los Angeles Rams beat the San Francisco 49ers today? Thursday Night Football picks, predictions, odds preview the NFL Week 5 game tonight.

Overview

  • San Francisco ruled out QB Brock Purdy (toe) and WRs Ricky Pearsall (knee) and Jauan Jennings (ankle/rib), adding to earlier losses of TE George Kittle (IR) and DE Nick Bosa (season-ending).
  • Mac Jones gets the start for the 49ers after winning two earlier fill-in games, totaling 563 passing yards with four touchdowns and one interception.
  • The Rams listed RT Rob Havenstein (ankle) and TE Tyler Higbee (hip) as doubtful after neither practiced this week.
  • Kickoff is 8:15 p.m. ET at SoFi Stadium on Amazon Prime Video, with local TV simulcasts, and the winner will hold at least a share of first place in the NFC West.
  • Betting lines shifted toward Los Angeles and most national expert picks now back the Rams following the 49ers' final injury report.