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1h ago

49ers Rule Out Brock Purdy for TNF at Rams as Mac Jones Starts

Injuries to San Francisco's top pass-catchers have shifted expectations toward Los Angeles.

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This first-down scramble in the first half against the Jacksonville Jaguars on Sunday at Levi’s Stadium may have been when 49ers quarterback Brock Purdy re-aggravated the injury to his big toe.
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Will Kyren Williams and the Los Angeles Rams beat the San Francisco 49ers today? Thursday Night Football picks, predictions, odds preview the NFL Week 5 game tonight.

Overview

  • Mac Jones gets the start after the 49ers officially ruled out Brock Purdy with a toe injury.
  • San Francisco also ruled out receivers Ricky Pearsall (knee) and Jauan Jennings (ankle/ribs), with George Kittle on injured reserve and Nick Bosa already lost for the season.
  • The Rams listed right tackle Rob Havenstein (ankle) and tight end Tyler Higbee (hip) as doubtful following a week without practice.
  • Both teams are 3-1, and the winner will take sole possession of first place in the NFC West.
  • Kickoff is 8:15 p.m. ET at SoFi Stadium, streaming exclusively on Prime Video, and betting markets and most expert picks have shifted toward Los Angeles after the 49ers' injury report.