Overview

• San Francisco officially ruled out quarterback Brock Purdy (toe) along with wide receivers Ricky Pearsall (knee) and Jauan Jennings (ankle/ribs) for Thursday at the Rams, and named Mac Jones the starter.
• On a short week and on the road at SoFi Stadium, the 49ers enter shorthanded at key passing spots after Purdy’s toe issue was aggravated in Week 4 and both starting receivers missed practice.
• Tyreek Hill sustained multiple-ligament knee damage and a dislocation and has already undergone surgery, with reports indicating his season is over for Miami.
• Reporter Gerry Dulac says Steelers starters Jalen Ramsey (hamstring) and Calvin Austin III (shoulder) could miss several weeks; Austin tweeted he was “all good” after a hospital visit in Ireland.
• The Browns benched Joe Flacco and will start rookie Dillon Gabriel against the Vikings in London, per NFL Network Insiders.