49ers QB Brock Purdy to Start Against Bills After Shoulder Injury

San Francisco aims to keep playoff hopes alive despite key injuries and challenging conditions in Buffalo.

Brock Purdy will return as the starting quarterback for the San Francisco 49ers after missing one game due to a right shoulder injury.
Purdy, who was listed as questionable earlier in the week, practiced fully on Friday and reported no setbacks ahead of the game.
The 49ers will face the 9-2 Buffalo Bills without several key starters, including left tackle Trent Williams, guard Aaron Banks, and defensive star Nick Bosa.
San Francisco enters the game with a 5-6 record and a 17% playoff probability, needing a win to stay in postseason contention.
The game is expected to take place under snowy conditions, adding another layer of difficulty for the injury-depleted 49ers.