Overview
- San Francisco announced the moves Saturday ahead of Sunday’s home game against the Cardinals at Levi’s Stadium.
- Guard Spencer Burford went on injured reserve with a knee injury and must miss at least four games, with surgery described as a possibility.
- Quarterback Adrian Martinez, a former UFL MVP who signed on Aug. 28 and has no NFL regular‑season snaps, was elevated from the practice squad.
- Mac Jones is expected to start again, while Brock Purdy was listed as questionable and could be inactive or designated as the emergency option.
- Receiver Malik Turner was elevated as depth with Jauan Jennings questionable and rookie Jordan Watkins ruled out, and the line remains thin with Ben Bartch already on IR.