Particle.news
Download on the App Store
4 ARTICLES
·
12h ago

49ers Open as Slight Favorites at Giants After Rookie RB Cam Skattebo’s Likely Season-Ending Injury

Oddsmakers lean toward San Francisco following the Giants’ backfield setback despite mixed model forecasts.

Will Christian McCaffrey and the San Francisco 49ers beat the New York Giants on Sunday? Will they cover the point spread? NFL Week 9 predictions, picks, odds preview the game on Nov. 2, 2025.

Overview

  • The game is Sunday, Nov. 2 at MetLife Stadium, airing on CBS at 11 a.m. MST with streaming available on Fubo.
  • BetMGM lists San Francisco −2.5 with a 48.5 total and roughly −150/+125 moneylines, while FanDuel posts −2.5 with a total near 46.5, and Niners Nation notes the 48.5 figure would be the 49ers’ highest projected total this season.
  • The Giants are 2–6 after recent losses and are likely without standout rookie running back Cam Skattebo for the season due to an ankle injury.
  • San Francisco enters 5–3 with uneven form, and analysts characterize the 49ers as the more balanced roster when healthy with playmakers such as Christian McCaffrey and George Kittle.
  • Predictions diverge, with The Arizona Republic, Dimers and Sports Betting Dime backing the 49ers, while ESPN’s model gives the Giants about a 56% chance to win.