Overview

• San Francisco fell 26-21 to Jacksonville, with Brock Purdy throwing two interceptions and losing a late fumble in his return.
• Purdy reported renewed soreness in his right big toe after the game, and Kyle Shanahan said his availability for Thursday is uncertain pending evaluation.
• Ricky Pearsall left with a right knee issue believed to be a minor PCL injury and Jauan Jennings exited with a rib injury, leaving both in question for Los Angeles.
• Special teams allowed an 87-yard punt-return touchdown and a long kickoff return, while the defense recorded no sacks or quarterback hits.
• Shanahan said officials admitted a first-half penalty error before a long Jaguars touchdown drive, and Mac Jones would likely start if Purdy cannot play.