Overview
- Mac Jones started with Brock Purdy inactive and threw for 347 yards, but an early interception set up a short Buccaneers touchdown drive.
- Jauan Jennings played through injuries and finished with one catch for seven yards, then had a heated sideline exchange with Kyle Shanahan that required staff intervention.
- After the game, Jennings said he is playing with five broken ribs along with high and low ankle sprains and shoulder issues.
- San Francisco activated safety Malik Mustapha to the 53-man roster for his season debut, with Ji'Ayir Brown expected to start alongside rookie Marques Sigle as Jason Pinnock’s role decreases.
- Linebacker Fred Warner was carted off with a broken and dislocated ankle that multiple outlets reported as season-ending, adding to a roster already missing Nick Bosa, George Kittle and Brandon Aiyuk.