Overview
- General manager John Lynch said on KNBR that Brock Purdy underwent additional tests and remains a true questionable, with the starter possibly not set until game day.
- After a day off, the team submitted an NFL-required estimated report listing Purdy as did not participate with turf toe and Mac Jones as a full participant with a knee sprain.
- Wide receiver Ricky Pearsall Jr. reported knee instability after the Jacksonville game and will be evaluated during the abbreviated week.
- Jauan Jennings, C.J. West, Yetur Gross-Matos, Jordan Watkins, and Robert Beal Jr. were estimated as non-participants, while Mykel Williams and Dee Winters were limited.
- Purdy played every snap in the 31–26 loss to the Jaguars, going 22-of-38 for 309 yards with two touchdowns and three turnovers.