Overview
- Kyle Shanahan said the team will not open Brandon Aiyuk’s 21-day practice window this week, and the wide receiver will miss the Week 10 game against the Rams.
- Aiyuk remains on the reserve/PUP list as he continues a prolonged recovery from an ACL and MCL tear sustained on Oct. 20, 2024.
- Under NFL rules, once a player’s practice window opens, the club has 21 days to activate him to the 53-man roster or move him to season-ending injured reserve.
- Shanahan described Aiyuk’s status as week to week, reflecting a cautious approach consistent with multi‑ligament knee rehabs.
- Ricky Pearsall’s availability for Week 10 is uncertain after a right‑knee PCL injury on Sept. 28, with Shanahan saying the team will evaluate him day by day; some coverage has suggested the club could consider aligning Aiyuk’s return with a Week 14 bye, but no decision has been announced.