Overview

• San Francisco opened 2025 at 1-0 with a 17-13 road victory over Seattle.
• Tight end George Kittle went to injured reserve with a hamstring injury and will miss at least four games.
• Kicker Jake Moody was waived after going 1-for-3 in Week 1, and the team is pursuing Eddy Piñeiro as a replacement, according to multiple reports.
• Quarterback Brock Purdy is dealing with toe and shoulder issues that leave his near-term availability in question.
• Analysts praised the result but flagged run-defense and interior line concerns, and external speculation tied the 49ers to potential depth moves, including tight end David Njoku and possible decisions involving Jauan Jennings, whose early shoulder evaluation was encouraging.