Overview
- Kickoff is 4:25 p.m. ET at Levi's Stadium in Santa Clara, with national television coverage on FOX and streaming options noted by providers such as Fubo and Sling.
- The 49ers enter at 6-3 and the Rams at 6-2, with Los Angeles riding a three-game winning streak.
- Backup Mac Jones starts for the 49ers in place of injured quarterback Brock Purdy.
- San Francisco will be without wide receivers Ricky Pearsall and Brandon Aiyuk for the matchup.
- The 49ers placed defensive lineman Mykel Williams on injured reserve and seek a season sweep after their Week 5 win over Los Angeles.