Overview

• The injury occurred in the first quarter when safety Ji'Ayir Brown rolled into Warner’s right ankle while tackling Rachaad White.
• Warner was placed in an air cast, carted off the field, and immediately ruled out as players from both teams urgently called for medical help.
• San Francisco lost 30-19 at Raymond James Stadium, conceding a season-high 30 points after Warner left the game.
• Bethune replaced Warner in the middle, with Dee Winters, Luke Gifford and Nick Martin part of the depth options going forward.
• The setback adds to a mounting list of key injuries — including Nick Bosa’s torn ACL and absences for Brock Purdy, George Kittle and Brandon Aiyuk — with the 49ers now 4-2.