Overview
- San Francisco (8-4) visits Cleveland (3-8) on Sunday, Nov. 30 at 1 p.m. EST at Huntington Bank Field, with the game on CBS.
- Reported betting lines list the 49ers as road favorites, opening around -6 with a moneyline near -258 and total of 42.5, while BetMGM has San Francisco by 5.
- USA TODAY’s panel largely picked the 49ers against the spread at -5.5, with a minority backing the Browns to cover.
- Rookie Shedeur Sanders is slated for a second start for Cleveland, as Brock Purdy enters off a three-interception game in his second start back from a toe injury.
- Cleveland’s defense ranks near the top of the league with Myles Garrett leading the NFL in sacks, while 49ers RB Christian McCaffrey leads in scrimmage yards heading into a highlighted matchup.