Overview
- San Francisco lost 26-21 at Levi's Stadium and dropped to 3-1 in Week 4.
- The defense produced zero sacks and zero quarterback hits for the first time since 2015 as the interception drought reached 11 games.
- Jacksonville ran for 151 yards, including a 48-yard Travis Etienne touchdown, while Trevor Lawrence stayed clean on quick throws.
- The turnover margin finished 4-0; Brock Purdy threw two interceptions, lost a fumble and said the mistakes start with him.
- Special teams conceded an 87-yard punt-return touchdown and a long kickoff return, and the 49ers face a short-week trip to the Rams.