49ers Face Rams Without Key Offensive Stars Kittle, Samuel, and McCaffrey

San Francisco grapples with significant injuries as they prepare for a crucial division match against the Los Angeles Rams.

Star tight end George Kittle is listed as doubtful with a hamstring injury, joining Deebo Samuel and Christian McCaffrey on the sidelines.
Running back Christian McCaffrey is on injured reserve with calf and Achilles issues, expected to miss at least three more games.
Wide receiver Deebo Samuel is out for two weeks due to a calf strain suffered in last week's loss to the Minnesota Vikings.
Defensive end Nick Bosa and cornerback Charvarius Ward are questionable for the game with rib and hamstring/knee injuries, respectively.
Backup tight end Eric Saubert is set to start in place of Kittle, while Jordan Mason will continue to shoulder the rushing duties.