49ers Face Multiple Injuries Ahead of Patriots Game

Deebo Samuel and Trent Williams are questionable, with key players like George Kittle and Christian McCaffrey also dealing with injuries.

Deebo Samuel practiced for a second straight day but remains questionable for Sunday's game against the New England Patriots due to a calf injury.
Trent Williams missed practice on Friday with a sore toe and is also listed as questionable for the upcoming game.
George Kittle, who missed last week's game with a hamstring injury, has no injury designation and is expected to play.
Christian McCaffrey, undergoing treatment for Achilles tendinitis, will miss at least two more games but is expected to ramp up rehab next week.
Safety Talanoa Hufanga and linebacker Dee Winters are questionable, while linebacker Curtis Robinson is out for the season with a torn ACL.