Overview
- Mac Jones led a 59-yard final drive to set up Eddy Piñeiro's game-winning kick as time expired.
- Robert Saleh's unit limited Arizona to 260 yards and 15 points to anchor the result.
- Christian McCaffrey totaled 27 touches for 140 yards, and Ricky Pearsall logged his second 100-yard game in three weeks.
- Nick Bosa exited in the first half and was ruled out with a knee injury as San Francisco played without Brock Purdy, Brandon Aiyuk, George Kittle and Ben Bartch.
- Before kickoff the 49ers elevated QB Adrian Martinez and WR Malik Turner and placed Spencer Burford on injured reserve.