Overview

• Christian McCaffrey has missed the first eight games of the season due to Achilles issues in both legs.
• 49ers GM John Lynch announced plans to open McCaffrey's 21-day practice window on Monday.
• San Francisco's rushing attack ranks fourth in the NFL, even without McCaffrey's contributions.
• Jordan Mason, who filled in for McCaffrey, suffered a shoulder injury but remains a key player.
• Rookie Isaac Guerendo has stepped up, showcasing his speed and potential in recent games.