Overview
- Kickoff is Sunday at 1 p.m. ET from MetLife Stadium on CBS with streaming on Paramount+.
- San Francisco will start Mac Jones at quarterback with Brock Purdy listed as questionable and expected to be available as a backup.
- The 49ers enter 5-3 and the Giants 2-6, with sportsbooks pricing San Francisco around -2.5 and the total near 48.5.
- New York is without rookie running back Cam Skattebo for the season, and rookie quarterback Jaxson Dart brings a noted rushing threat the 49ers must contain.
- San Francisco’s defense has been thinned by major injuries to stars Nick Bosa and Fred Warner, prompting a recent trade for pass rusher Keion White.