Overview
- Gross-Matos returns from a hamstring injury that sidelined him since Week 5.
- San Francisco elevated cornerback Eli Apple and linebacker Eric Kendricks from the practice squad for the game.
- Shanahan said Kendricks practiced this week with no conditioning concerns.
- The 49ers ruled out Renardo Green (neck), Ricky Pearsall (knee/ankle) and Kurtis Rourke (knee).
- Indianapolis activated defensive tackle DeForest Buckner from injured reserve for his first game since Week 9.