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15-Minute HCV RNA Test Validated With 100% Agreement in Johns Hopkins Study

Independent results matching commercial lab platforms point to same-visit diagnosis that could speed treatment initiation.

Overview

  • Northwestern adapted its DASH rapid PCR system, originally built for COVID-19, to detect hepatitis C from whole blood at the point of care.
  • The Journal of Infectious Diseases published the study describing a 15-minute runtime and detection across all six major HCV genotypes.
  • Reported performance in the study included approximately 99% sensitivity and 100% accuracy compared with commercial laboratory tests.
  • Johns Hopkins independently tested 97 clinical specimens and found 100% agreement with standard diagnostic platforms.
  • Current FDA-cleared point-of-care HCV testing requires 40–60 minutes and lab-based pathways often add days or weeks, which can prevent timely treatment starts.