Francis Aurelio deSouza is an American entrepreneur and business executive. He is co-founder of SynthLabs, and a member of the Board of Directors of Deel Inc.
He was previously the chief executive officer of Illumina. Before Illumina, deSouza was president of products and services at Symantec. He joined Symantec in 2006 when Symantec acquired IMlogic, where deSouza was founder and CEO.