Dr. Henry A. Wise Jr. High School is a public high school in the Westphalia census-designated place in unincorporated Prince George's County, Maryland, United States, with an Upper Marlboro postal address. A part of the Prince George's County Public Schools, it opened in the Fall of 2006. Its namesake was doctor Dr. Henry A. Wise Jr., the first African-American doctor admitted to practice at Prince George's Hospital.