Osteopontin, also known as bone /sialoprotein I, early T-lymphocyte activation, secreted phosphoprotein 1, 2ar and Rickettsia resistance, is a protein that in humans is encoded by the SPP1 gene. The murine ortholog is Spp1. From Wikipedia
Researchers report up to 56% neuron loss in impact‑prone cortex of athletes under 51, predating detectable tau pathology.
