Major Motoko Kusanagi, or just "The Major", is the main protagonist in Masamune Shirow's Ghost in the Shell manga and anime series. She is a cybernetic human, augmented with a synthetic "full-body prosthesis". From Wikipedia
Atsuko Tanaka, celebrated for her roles in 'Ghost in the Shell' and 'Naruto,' succumbed to an undisclosed illness after a year-long battle.
