Riken (理研, stylized as RIKΞN, English: /ˈrɪkɛn/) is a large scientific research institute in Japan. Founded in 1917, it now has about 3,000 scientists on seven campuses across Japan, including the main site at Wakō, Saitama Prefecture, just outside Tokyo. Riken is a Designated National Research and Development Institute, and was formerly an Independent Administrative Institution. Riken conducts research in many areas of science, including physics, chemistry, biology, genomics, medical science, engineering, high-performance computing and computational science, and ranging from basic research to practical applications with 485 partners worldwide. It is almost entirely funded by the Japanese government, and its annual budget is about ¥88 billion (US$790 million).[when?]