U.S. Route 42 (US 42) is an east–west United States highway that runs southwest–northeast for 350 miles (560 km) from Louisville, Kentucky to Cleveland, Ohio. The route has several names including Pearl Road from Cleveland to Medina in Northeast Ohio, Reading Road in Cincinnati, Cincinnati and Lebanon Pike in southwestern Ohio and Brownsboro Road in Louisville. Traveling northeast, the highway ends in downtown Cleveland and traveling southwest ends in Louisville. Interstate 71 (I-71) fully supplanted US 42 as an interurban highway in the early 1960s, relegating US 42 to its current role as an ordinary town-to-town surface road. Additionally, I-71 passes through Columbus, where US 42 avoids Columbus completely. It remains intact as a route; no part of it has ever been diverted to any Interstate highway. It is not the "parent" of any US route with a related number. In spite of its even number, US 42 is posted north–south in Ohio. From Wikipedia
