Coordinates: 40°49′25″N 73°56′38″W / 40.823634°N 73.943825°W / 40.823634; -73.943825 145th Street is a major crosstown street in the Harlem neighborhood, in the New York City borough of Manhattan. It is one of the 15 crosstown streets mapped out in the Commissioner's Plan of 1811 that established the numbered street grid in Manhattan. It forms the northern border of the Sugar Hill neighborhood within Harlem.