Uracil-DNA glycosylase is an enzyme. Its most important function is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosidic bond and initiating the base-excision repair pathway. From Wikipedia
A viral vector delivering a uracil glycosylase inhibitor restores APOBEC1’s antiviral editing to block HSV-1 replication in the brain.
