Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases are enzymes that catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. From Wikipedia
The ruling rests on phase 3 INDIGO data demonstrating a substantial progression-free survival advantage.
