Prostaglandin E₂ receptor 2, also known as EP₂, is a prostaglandin receptor for prostaglandin E2 encoded by the human gene PTGER2: it is one of four identified EP receptors, the others being EP₁, EP₃, and EP₄, which bind with and mediate cellular responses to PGE₂ and also, but with lesser affinity and responsiveness, certain other prostanoids. From Wikipedia