The Black Death was a bubonic plague pandemic that occurred in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people perished, perhaps 50% of Europe's 14th century population. From Wikipedia
Sequential carbon-nitrogen isotope analysis reveals that childhood famine enhanced odds of reaching young adulthood before reversing into higher mortality after age 30, spurring fresh urgency for robust early-life nutrition initiatives.