Overview

• A JAMA Network Open paper published June 9 analyzed 479,723 UK Biobank participants from 2012 to 2025 and linked regular cycling to a 19% lower dementia incidence.
• Alzheimer’s risk fell by 22% among cyclists, with young-onset dementia cases up to 40% lower compared with inactive commuters.
• Noncarriers of the APOEε4 gene saw a 26% dementia reduction from cycling while carriers still benefited by 12%.
• Brain scans indicated cycling bolsters hippocampal volume and boosts cerebral blood flow as it combats inflammation.
• Lead researchers urge governments to promote bike commuting as an accessible strategy for preserving cognitive health.