Overview

• The nanoneedle patch, featuring tens of millions of hair-thin needles, painlessly penetrates living tissues to sample molecules without cutting or removing tissue.
• Extracted molecular fingerprints including lipids, proteins and mRNA are analyzed through mass spectrometry and artificial intelligence to gauge tumor presence, treatment response and disease progression.
• In tests on human brain cancer biopsies and mouse models, the device produced high-resolution biochemical profiles without causing tissue damage.
• The technology can deliver actionable results within 20 minutes, offering potential for real-time guidance during surgeries and integration into devices like bandages, endoscopes and contact lenses.
• Investigators plan clinical trials to evaluate the patch’s safety and effectiveness in patients following its preclinical validation.